- Brand: Lysto
- Active Ingredient: Sildenafil Citrate
- Treatment: Erectile Dysfunction
- Manufacturer: La Santé
- Country of Manufacture: Colombia
Review and Description
Sildenafil is the drug of choice in the treatment of erectile dysfunction in men. It works primarily by enabling the penis to have long lasting erection during sexual stimulation.
Sildenafil is categorized as an anti-erectile dysfunction drug and is known as phosphodiesterase type 5 inhibitor. Phosphodiesterase type 5 causes the breakdown of a chemical called Cyclic GMP. Cyclic GMP causes the blood vessels in the penis to dilate thus allowing an erection to occur. With phosphodiesterase type 5 inhibited, GMP is retained, thereby allowing a longer state of erection.
Since the discovery of sildenafil through the favorite brand Viagra, many other pharmaceutical companies heed the call to lower drug cost and make sildenafil more accessible to the public. In Colombia, Le Sante came up with a unique concept to sell sildenafil, that is an oral spray form (patented as Lipospray®) and with brand name Lysto.
Laboratories La Santé is a pharmaceutical giant mainly focusing its operation in Latin American countries such as Colombia, Guatemala, Argentina, and other South American territories. It is Colombia’s #1 exporter of medicine. The company boasts of its 4 production plants, 1 in Venezuela and 3 in Colombia.
Lysto is registered with Colombia’s National Institute of Food and Drug Monitoring (locally called ‘INVIMA’).
A Google search of Lysto would lead you to limited results if you search its availability in different parts of the world, though it is a rare formulation of Sildenafil. Searching further, however, there is no reliable customer reviews and feedback regarding the firsthand use of Le Sante’s Lysto. You are warned on the possible adverse reaction of this drug especially when consumed without physician’s recommendation. Also, without any notable reviews for the drug, potential consumers would not have any idea on the drug’s efficacy. More alarmingly, this spray formulation of Sildenafil is not approved by US-FDA and other remarkable regulatory authorities for example UK-MHRA, TGA Australia etc. You are warned of these repercussions and we encourage you to seek medical advice to determine if this product suits you.
Pricing and Dosage
Lysto is sold as 18.38mg/20ml metered spray pump. Each spray dispenses 0.68ml, which gives 12.5mg per spray. Each bottle is sold at around 24-25 US Dollar.
The recommended starting dose of sildenafil is 50mg and a maximum of 100mg per day. The dose could be adjusted based on the strength the patient is comfortable with. As for the oral spray form, it is presumed that 4 pumps on the spray bottle would deliver at least 50mg of sildenafil.
How to Buy Lysto Online
Lysto is available through several online stores mainly operating within Latin American countries such as Colombia. It is not known if these stores could ship and sell Lysto outside Latin America.
It is understood that sildenafil would require a physician’s prescription before dispensing. However, we are not aware if Latin American countries like Colombia would allow selling Lysto even without a doctor’s prescription.
How to Use
Lysto is used as an oral spray. Unlike the conventional sildenafil tablets, the oral spray form would no longer require water intake. The bottle is sprayed to the oral cavity, particularly under the tongue to be absorbed by the body. Usually, the tablet form would require its user to take each pill at least 30 minutes to an hour before sexual stimulation. Due to lack of resources, however, it is not known if Lysto would take effect sooner or later than that of the tablet form.
Usual sildenafil side effects would include a headache, facial flushing, temporary changes in vision and ringing in the ear. These symptoms may fade with further use.
More serious side effects would include chest pain, the difficulty of breathing, blindness, and priapism- a state of erection that would last for more than 4 hours. These are emergency situations and would require doctor’s intervention as soon as possible.
People taking nitrates or any antihypertensive drugs would not be advised to concurrently use sildenafil with these drugs, as blood pressure might dramatically decrease.
People with HIV undergoing antiretroviral therapy, mainly using protease inhibitors like ritonavir, are not encouraged to practice concurrent intake with sildenafil. Protease inhibitors may increase sildenafil blood levels to 11-folds, thereby increasing fatal side effects.
Le Sante Pharmaceuticals made it easier for consumers to use sildenafil with their revolutionary formulation of a spray-type oral sildenafil, marketed as Lysto. This formulation gets rid of the need to drink water to ingest the pill. As it is taken through oral spray form, it is presumed that the drug is absorbed sublingually (or through under the tongue), which means the drug will deliver its intended effect sooner than the tablet form.
Browsing for information about the proper use of this drug was a difficult task, because, Lysto is NOT listed on La Sante’s official website. Second, other resources, such as packaging and registration information with Colombia’s National Institute of Food and Drug Monitoring was not found. Nonetheless, La Sante’s reputation in the pharmaceutical industry is undisputable.
Despite the convenience of using Lysto through its oral spray form, we would not recommend its use for those who are not within Latin America, who do not have precise information about its intake. Because of this, we give it a 1 out of 5 stars.